Since the old forum is gone, I’ll repost this for your information.
Volume Shadow Copy or “VSS” (provided by Windows 2003 / 2008 / Vista / 7) which allows users to restore previous versions of files (also used for System Restore Points) cannot be used on Drobo!
It can be activated and Windows thinks all is working fine, but most files I’ve restored afterwards got corrupted.
Drobo Support has been notified about my experience months ago and said, they’ll research that (never heard from them).
So, if you plan to use Volume Shadow Copy, be warned!
The issue has been confirmed by DRI in 07/2010. I expect additional information in the Knowledge Base soon.