I have a 5D with 5x4TB disks. 2 Volumes (one main and the other time machine).
I was running out of space and replaced one by one 3 disks with 6TB ones.
During and after replacing the 2nd one I notices spontaneous panic reboots on my Mac.
Drobo was running OK but the Mac acted like never before.
I disconnected the Drobo (and am now reverting to all 4TB disks) and the Mac was stable again.
Supposedly it should work with 6TB disks. This must be a Drobo software/driver issue.
Really unhappy.