Cleaning Drobos & Hot drives

I have 2 older 1st gen Drobos, and it seems like the drives are getting warmer. Is there any reason NOT to take it apart, clean out the dust bunnies, & upgrade to a higher capacity fan(same power draw)? Any weird anti-tamper screws on the inside? I do not have any warranty to void at this point. Everything is ok at this time, I just finished cleaning some LARGE dust bunnies from my computers, and would think the Drobo needs some cleaning and TLC after 2?3? years of running non-stop!

My Drobos are still under DroboCare, so I just give them a blow with the air duster. Surprising how much dust accumulates.