5N2 - cant save settings or connect to shares

I am unable to connect to any of my shares on my 5N2.
Nor can I add any new users or modify share access.
Drobo Dashboard gives a error message when I try any of the above.

All lights are normal, green for all drives and power, only one blue light for capacity level and drive health is Good.

I manually loaded the latest firmware 4.2.2 and have rebooted numerous times with no luck.
Submitted a support ticket and uploaded diagnostic files.

Anyone had this issue before?